Semi-Synthetic Macrolide Antibiotic Acevor (Roxithromycin)
Roxithromycin is also known as Acevor. It is a semi-synthetic macrolide antibiotic which is used for the treatment of infections in soft tissues, chest, urinary and respiratory tract. It works by preventing the growth of the infectious bugs by interrupting their protein production.
USES of roxithromycin
Roxithromycin is used to treat acute pharyngitis – sore throat and difficulty in swallowing, sinusitis, tonsillitis, acute bronchitis- cough due to infection in bronchi, pneumonia- infection in lungs characterized by malaise, fever and headach; chronic bronchitis, non gonococcal urethritis, and impetigo- bacterial infections which produces sores on the skin and soft tissues infections. The inactive contents present in this drug are: purified talc, colloidal anhydrous silica, magnesium stearate, povidone, hypromellose, maize starch, anhydrous glucose, propylene glycol and titanium dioxide. This drug like other antibiotics does not treat viral infections like common cold, flu etc.
Roxithromycin 150mg tablets
HOW TO USE roxithromycin
The recommended dosage for adults is 150 mg twice in a day or 300 mg once for 5 to 10 days. It is available in the form of tablets and is meant for oral administration on an empty stomach.
SIDE-EFFECTS of roxithromycin
Nausea, abdominal pain, vomiting, diarrhea, indigestion, fainting, loss of appetite, altered taste, ringing in the ears, fatigue, constipation and flatulence are some common side effects caused during the intake of roxithromycin. Weakness, dizziness, vertigo, headache, abdominal pain, cramps in abdominal muscles, fever, hallucinations, changes in heartbeat and uneasiness may also occur. Some symptoms of liver disease such as increased values of liver enzymes, dark urine, yellowish skin or eyes, stomach ache and liver inflammation may also be seen. Some other side effects may result into allergic reactions such as changes in blood counts, oral thrush, rashes, eosinophilia, wheezing, coughing, itching, vaginal thrush, hives, difficulty in breathing, redness and swollen face, tongue or throat. Some other side effects which are not mentioned above may also occur in some patients. Inform your physician or doctor immediately if you observe any of these aftereffects.
CONTRAINDICATIONS of roxithromycin
Roxithromycin is contraindicated in patients having the history of: unusual heart rhythm, impaired kidney function, liver impairment like hepatic cirrhosis with ascites or jaundice and allergy to macrolide antibiotic. Don’t consume roxithromycin if you are hypersensitive to it or any other macrolide antibiotic such as clarithromycin, azithromycin or erythromycin. Don’t use this medication if you are taking some drugs for migraine known as ergot alkaloids like dihydergot, cafergot or ergodryl. The medicine may contain certain inactive ingredients which may be responsible for some allergic reactions. Drug interactions alter the mechanism of action of a certain drug. Roxithromycin may be affected by some medicines like warfarin, theophylline, ergotamine, disopyramide, digoxin, cisapride, midazolam, cyclosporine, terfenadine and astemizole. Tell your doctor if you are taking any of these drugs along with roxithromycin.
ROXITHROMYCIN DURING Pregnancy
Don’t take this medicine if you’re pregnant or planning to be pregnant. Don’t consume roxithromycin unless you have discussed about the benefits and risks of this medicine with your physician or doctor. Avoid taking this drug whilst breast-feeding.